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Completed Projects

MEDICAL AND ENVIRONMENTAL BIOTECHNOLOGY

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Funded Projects

Electronic Olfaction for Biotech Applications: Principal Investigaror: Dr. V. Krishna Murthy. The Objective of the Project: Applications for E-Nose in the field of Biotechnology and develop working framework/methodology for soil fertility testing; monitoring of cheese ripening; quality estimation of spice (cardamom) and waste water quality estimation.

Microbial Mediated Tolerance assays for selected Xenobiotic Elements of Environmental Biotechnological importance: Principal Investigator-Dr. Seema Tharannum – ,UGC minor research project of amount Rs.1,50,000/- with ref no. MRP(S)-705/10-11/ KABA037/UGC_SWRO. ( 2011-2013)

Isolation and characterization of chromium tolerant bacteria in industrial effluents with special reference to utilize them as bioremedial agents: The project dealt with enrichment and isolation of the microbial system possessing degradation abilityf from the effluent samples of electroplating industries. This followed Biochemical investigations with reference to chromium and establishing a system of Bioremediation, specific to Chromium bioremediation testable laboratory scale. The study showed maximum tolerable

concentration for the newlymicroorganism detected ranged between 1750 – 30500 mg/L of chromium . The Study conclusively demonstrated that bacteria Bacillus subtilis, Bacillus amuloliquefaciens and Micrococcus luteus in an immobilized consortia would be a novel combination biomaterial for removal of chromium VI from electroplating industrial effluent.

Evaluation of efficiency of bacterial species as bioremediating agents for endosulfan as a representative pesticide: Principal investigator: Dr. Sarah Sunitha; UGC minor research project of amount Rs.1,80,000/- with ref no. MRP(S)-704/10-11/KABA037/UGC_SWRO: The three new strains of microorganisms designated as PES 3a,3b and 3c were isolated , cultured and their potential to remediate endosulfan pesticide was studied. Strain 3a and 3b showed 98% homology with 16srRNA and 3b and 3c showed 100% homology . The potential degree of Endosulfan remediation was PES 3a> 3c>3b.. Endosulfan was found to be slow degraded when compared to other isomers of endosulfan sulfate. The strains showed degradative activity in concentrations as high as 200mg/L of endosulfan.

Development of Ecofriendly treatment of biomedical waste using epigeic earthworms. Principal Investigator: Dr. M S Dinesh; Co Investigator Dr. V Krishna Murthy – for an Indian Society for Hospital Waste Management, New Delhi . Budget Rs. 65,000/: In the present study, the biodegradable part of infectious bio-medical waste collected from a local hospital and was subjected to vermicomposting using epigeic earthworm species – Eisenia fetida, Eudrilus eugeniae and Perionyx excavatus. The tank efficiencies were: Monoculture tank of Eisenia fetida > Polyculture tank >Monoculture tank of Eudrilus
eugeniae> Monoculture tank of Perionyx excavatus.

Research Project Summaries of PhD Scholars, Status : PhD degree awarded.

Scholar: Dr. Dhiraj Giri; Supervisor: Dr. V. Krishna Murthy

Multivariate modelling approach in aerosol quantification prediction and effect studies with particular reference to respirable particulate pollution in an urban valley environment: The study had objectives of understanding of the air quality of valley, pollutants and their dispersion, translocation and distribution of respirable particulate pollution; investigate the characteristics and determinants of the influence of meteorological parameters and identify appropriate applied mathematical tools to predict and quantify air pollution.

Scholar: Mr. Prashantha Karunakar; Supervisor: Dr. V. Krishna Murthy

Crystal structure and molecular docking analysis of furan derivatives having pharmaceutical significance and determination of assembly of chains in protein targets: This project work is an account of the crystal structural analysis and docking studies of a few furan derivates and conformational studies of other organic compounds of biological and pharmaceutical interest.

Scholar: Mr. Ravindranath B S; Supervisor: Dr. V. Krishna Murthy

Study of causative agent for infective chronic obstructive pulmonary disease with reference to chlamydophila pneumonia through bioinformatics approach: The present study mainly focuses on identifying novel therapeutic targets of pathogen using various strategies by effectively utilizing the available genomic information of pathogens.The computational approach adopted in this study was effective to identify the putative therapeutic targets which will provide a deeper insight to the genes/proteins that are involved in pathogenicity of C.pneumoniae.



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